I run dual 7" in my truck in a sealed box, but they are very close together, the flanges are only about 2" apart ( so center to center would be ~9"). Either way it sounds great and I have very little nulls in my midbass response.
I'm thinking of doign the same thing in my car but in this case the two 7" center to center would be more like 16" apart.
I think I have read, and from what I know of theory, that I risk getting some weird modes/cancellation. I would be playing 80-250, no higher.
And no I don't have the channels to run them independently they would be wired in parallel and on the same phase/timing.
Its easy to say just try it, but we are talking 8-10 hours of having to redo fabrication if it doesn't work out, so just trying to think it through.
I imagine there is some "math" that tells me where this might become a problem. Advantages are cone area without the required depth of a big speaker, and possibly rmoving the standard mid bass null most cars have. No need to touch base on ohms or power I have that figured out.
The other option is a single 9.5" driver which I guess by all considerations would be superior. Except for the "giant speaker exploding out of the door and hitting your leg" part.